Your Brain Will Age Prematurely If You Don't Sleep Optimally


Rohit Kulkarni

Rohit Kulkarni

Nov 04, 2024


 Sleep is important and the knowledge around the same is commonplace, so is the detriments of pulling an all-nighter!

Your Brain Will Age Prematurely If You Don't Sleep Optimally
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The Hidden Dangers of Sleep Deprivation

As per a recent study published in the Journal of Neuroscience, lack of sleep or all-nighters not only impairs the cognitive function, increase anxiety, and decrease alertness, but also it ages your brain!

The study revealed that just one night of sleep deprivation can alter brain structures, making them appear older.

To understand things better, brain aging involves structural and functional changes which leads to diminishing cognitive abilities. Sleep allows our brains to recuperate by consolidating memories, eliminating toxins, and forming new neural connections. Lack of sleep, on the other hand, hinders these processes and leads to eventual cognitive impairment.

The sample of study involved 134 healthy participants, ages 19 to 39, with an average age of 25.3 years. 4 sleep conditions were tested:

1.           Total sleep deprivation (no sleep)

2.           Partial sleep deprivation (three hours)

3.           Chronic deprivation (five hours over five days)

4.           Control group that got eight hours.

The results of the study were shocking since those who experienced total sleep deprivation showed a brain age increase of one to two years after just one night without sleep, whereas on the other hand, the other groups did not show significant changes.

Much to the fortune of those who pulled an all-nighter, a full night of sleep can reverse these aging effects.

Though the narrow age range of participants as well as study’s short duration do have some limitations, but the study underscores the need for further research to explore the long-term impacts of sleep deprivation across various age groups and sleep patterns.

Other Impacts: Increased Dementia Risk and Impact on Mental Health

There are other detrimental effects in addition to brain aging. Sleep deprivation can elevate the risk of developing dementia. While awake, our brains accumulate toxins linked to neurodegeneration. The glymphatic system helps clear these harmful substances, including amyloid beta-protein, associated with Alzheimer’s, but it functions optimally during sleep.

Mental health is adversely affected by sleep deprivation as well. Sleep and mental health are directly related to each other. Those who get inadequate sleep, report mood disturbances and increased stress.

Sleep deprivation hyper-activates the amygdala, which is responsible for emotional processing, impairing your ability to accurately interpret emotions and increasing anxiety and depressive symptoms.


Rohit Kulkarni
Rohit Kulkarni
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