South Indians Face Greater Risk Of Heart Attack - Research


Mohul Ghosh

Mohul Ghosh

Dec 05, 2025


Nowadays, heart disease is one of the biggest health threats faced in the country and these latest findings suggest that risk may not be evenly distributed across the population. 

South Indians Face Greater Risk Of Heart Attack - Research

South Indians May Face Greater Risk of Heart Disease

A recent Bengaluru-based investigation highlighted the striking genetic and regional differences highlighting certain groups which are at considerably higher risk of developing serious cardiac conditions.

Moving ahead, this study has sparked major discussion about whether South or North Indians face a greater vulnerability to dangerous forms of heart disease.

The findings are challenging long-held assumptions and raising urgent questions about screening and prevention. 

Considering the present situation, it has become essential to understand how ancestry, geography and lifestyle intersect to influence cardiac health and to get personalized care and nationwide prevention strategies.

It appears that the coronary heart disease mortality rates are significantly higher in many southern Indian states when compared with several northern and central regions as per a peer-reviewed study in PubMed.

This is true even after adjusting for conventional risk factors such as diet, smoking and blood pressure.

Basically this research highlights substantial regional disparities in cardiovascular burden and suggests genetic, metabolic and lifestyle factors may interact differently across populations, shaping overall vulnerability in complex ways.

Moving ahead, this research talks about who is more likely to suffer from dangerous heart disease.

The individuals of South Indian origin may show a stronger genetic predisposition to certain serious cardiac conditions, particularly hypertrophic cardiomyopathy as per recent findings from a multi-centre South Indian study led by researchers in Bengaluru.

 Moving ahead, this condition involves abnormal thickening of the heart muscle and can progress silently before leading to heart failure or sudden cardiac arrest.

It appears that the specific genetic variants linked to this condition appear more frequently among South Indians compared with other groups, highlighting the importance of population-specific screening rather than relying solely on data derived from Western populations according to the study.

Why Would This Happen?

This could be caused by certain harmful mutations and unique genetic profiles which may be more common among South Indians, increasing the likelihood of developing life-threatening heart conditions as suggested by the Bengaluru study.

These findings highlight the importance of regional genetic research, improved screening programs, early intervention strategies, and greater awareness to help identify high-risk individuals more effectively.

Besides this, the south Asians, including many South Indians, exhibit disproportionately higher rates of insulin resistance, abdominal fat accumulation and atypical cholesterol patterns.

It appears that these are the key risk markers that strongly contribute to coronary artery disease progression.

In addition to this, urban lifestyles, long working hours, stress, low activity levels and processed food consumption exacerbate predisposition, making prevention more difficult if risk is not recognised early.

How To Prevent Or Reduce Heart Disease Risk ?

In order to achieve this, the individual needs to maintain a heart-healthy diet rich in whole foods, vegetables, fruit, nuts and whole grains, exercise regularly and reduce sedentary behaviour through daily activity.

They also need to monitor blood pressure, cholesterol, sugar levels and body composition while managing stress and prioritise consistent sleep routines daily.

The individual needs to avoid smoking and excessive alcohol consumption, the discussion of family history with a healthcare professional and consider screening if risk factors exist.

We need to understand here that awareness is the first defence, and informed action remains the strongest tool in preventing avoidable heart disease.

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Mohul Ghosh
Mohul Ghosh
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